Meanwhile drugmaker Gilead Sciences said in a statement that a five-day course of the remdesivir sped up recovery in moderately ill patients with pneumonia from COVID-19. The drug has reportedly been administered to United States President Donald Trump, who was announced COVID-19 positive last Friday.BPOM head Penny K Lukito expects that they EUA issuance will help accelerate access to those drugs for hospitals treating COVID-19 patients.“Hopefully, the drugs will help improve COVID-19 recovery rates and bring down the mortality rate from the pandemic,” Penny said in a statement on Tuesday.She said she hoped doctors and health workers would cooperate in monitoring the efficacy and safety of those drugs under pharmacovigilance.The World Health Organization defines pharmacovigilance (PV) as the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem.All pharmacovigilance reports will be received by the BPOM and evaluated periodically.If there is an increasing trend of side effect, the BPOM will immediately communicate the risk and revoke the EUA, the statement further said.Since March, the BPOM periodically searches the internet to detect any disinformation regarding drugs claimed to cure COVID-19. It had found more than 46,000 links, including 2,645 links of people illegally selling what they claim are COVID-19 drugs.Upon such findings, the BPOM recommends that the Indonesian E-Commerce Association (IDEA) and Communications and Information Ministry take down those links. (iwa) Topics : Data from the Office of the Coordinating Maritime Affairs and Investment Minister show that the government had previously given contractors the go-ahead to import COVID-19 medication such as remdesivir, favipiravir, oseltamivir and lopinavir-ritonavir, all of which will be distributed directly to hospitals treating coronavirus patients.The data show that, by the end of 2020, the government expects to secure 670,000 vials of remdesivir from foreign sources, but it also expects the drug to be manufactured in the country starting in November.In late September, Reuters reported that a late-stage study by Fujifilm Holdings Corps of its antiviral drug Avigan showed that it reduced recovery times for COVID-19 patients with nonsevere symptoms.The Phase 3 clinical study of 156 patients in Japan showed that those treated with Avigan improved after 11.9 days, versus 14.7 days for a placebo group. The Food and Drug Monitoring Agency (BPOM) has issued emergency use authorization (EUA) for two antiviral drugs, favipiravir and remdesivir, to treat COVID-19 patients.The BPOM also granted permits in September to several pharmaceutical companies to produce the drugs. PT Beta Pharmacon (Dexa Group) received a permit to produce favipiravir, locally sold under the Avigan brand. State-owned drug manufacturer PT Kimia Farma received the permit to produce a generic favipiravir product, tempo.co reported on Wednesday.Meanwhile, permits to produce remdesivir have been granted to PT Amarox Pharma Global, which is a subsidiary of India’s leading generic drug maker Hetero, as well as to state-owned pharmaceutical firm PT Indofarma and local private firm PT Dexa Medica. Editor’s note: This article is part of a public campaign by the COVID-19 task force (Satgas COVID-19) to raise people’s awareness about the pandemic. #covid19taskforce #mothermessage #wearmask #keepyourdistance #washyourhand #socialdistance #avoidcrowd #usesoap
Field said: “We hope and expect we will never again see a company like BHS be able to come up with a 23-year recovery plan for its pension fund, and certainly not that it would take the regulator two years to really begin to do anything about it.”Among the committee’s proposals are:“Nuclear deterrent” powers for TPR to fine employers three times a pension fund’s deficit if it refuses to engage with trustees;TPR to be given powers to intervene in corporate actions if they are perceived to threaten a pension fund;The establishment of an “aggregator fund” to take on small pension funds – potentially to be run by the PPF;An overhaul of the “regulated apportionment arrangement” framework to make it easier for schemes to separate from employers where appropriate;The introduction of a form of conditional indexation to allow stressed schemes to reduce liabilities;An extension of DB members’ ability to take their benefits as lump sums.“To prevent another BHS, we need to have the means to nip inevitable disasters like this one in the bud,” Field added. “We hope the government will consult on the package of measures we propose, which would go a long way, without resorting to any new reams of red tape, towards doing just that.”Next year, the government will publish a green paper aimed at pension reform, according to the pensions minister Richard Harrington.TPR criticismThe committee’s report criticised TPR’s approach to stressed schemes and anti-avoidance, arguing that it seemed “reluctant” to use some of its powers.The committee added: “We get the impression [TPR] can be somewhat aloof in dealing with trustees when it is well placed to provide timely, informal guidance.”TPR has announced a review of its regulatory approach.Chris Martin, an independent trustee and chair of the BHS trustee board, told the committee: “I have a definite sense that there is sometimes a reluctance to use the powers because it might provoke challenge. To my mind, a regulator should be challenged. It develops [the] use of its powers by being challenged.”Lesley Titcomb, TPR chief executive, said: “We note [the] recommendations and will consider them carefully. We continue to discuss options with the Department for Work and Pensions for the legislative and regulatory framework for workplace pensions, and how this might be improved, ahead of the green paper, which will consider the future of pension funding, the regulatory framework and TPR’s powers.”Intervention powersTPR should be able to intervene and stop corporate-level activity by a scheme’s sponsor if it is judged to be a threat to the funding of the scheme, the report said. This would include mergers, acquisitions and dividend payments.Given such powers, the politicians argued, TPR could have prevented the sale of BHS last year without a plan to fund the pension scheme.However, in her evidence to the committee, Titcomb warned that such powers would have “resource implications” for the regulator.“Granting TPR the power to block a corporate transaction was ‘superficially attractive’, but the situations in which it applied would need to be ‘very tightly defined’,” the report said.The regulator should also be “tougher” on schemes’ deficit-recovery plans, the report said – “it should not be shy or slow in imposing a contribution schedule when a sponsor is not taking its responsibilities seriously.”The committee added: “There is clear evidence many sponsors could give greater immediate support to their pension schemes.”The PPFAlso among the committee’s recommendations was the introduction of an “aggregator fund” to aid small schemes that struggle to get access to buyout.The report said there was a “very strong case” for creating a vehicle to consolidate such schemes, potentially to be run by the PPF.As well as Harrington, former pensions ministers Steve Webb and Baroness Ros Altmann backed the concept.Harrington said the fund would not cut pension payments (as the PPF does with non-retired members), and would provide benefits of scale and “a chance of getting better returns”.Alan Rubenstein, chief executive of the PPF, told MPs his organisation was willing to take on the task if requested.However, he warned that the details of an aggregator fund would be difficult to iron out because of differing funding levels and the need for deficits to be closed.Joanne Segars, chief executive of the Pensions and Lifetime Savings Association (PLSA), backed consolidation plans. She said: “As the committee recognises, creating consolidators is a complex task where the details matter. We are actively investigating the pros and cons of the spectrum of consolidation options including an aggregator fund or funds model.”The PLSA’s DB Taskforce is to publish its own recommendations in March.Responding to the report this morning, Rubenstein said: “We’re pleased to see that a number of our suggestions have been taken on board, particularly around anti-avoidance fines to improve oversight of corporate transactions.“The recommendations of this considered report are timely and will hopefully set the standards for companies to ensure their pension scheme members are protected now and in the future. We will give full consideration to those recommendations which relate to the PPF.”The full report is available on the committee’s website. A group of British politicians have called for radical reform of the defined benefit (DB) sector to avoid future scheme failures.The Work and Pensions Committee has called for a series of new powers for the Pensions Regulator (TPR), including “nuclear deterrent” fines to force employers to confront their pension shortfalls.The proposed reforms come as TPR is attempting to resolve the future of the British Homes Stores (BHS) pension scheme, and the saga formed the backdrop to the inquiry.Frank Field, chair of the committee, argued that many of the proposals would have prevented the scheme from developing a large deficit and facing being absorbed into the Pension Protection Fund (PPF).
Sonardyne International has appointed Graham Brown as its new managing director.Graham, who takes over the role from John Ramsden on April 01, has served on Sonardyne International’s board from 2008, most recently as sales and marketing director and deputy managing director.John, who has been Sonardyne International’s managing director since 2009, is staying within the Sonardyne, taking the role of CEO of Sonardyne Group, the newly formed parent company of Sonardyne International and its sister companies, Chelsea Technologies, EIVA, Wavefront and 2G Robotics.“This is an exciting time for Sonardyne International,” said Graham. “Looking beyond the current, uniquely challenging business climate, we’ll continue to grow organically, in terms of our people, our technology offering and the global markets which we support – while upholding the service and support that we’re renowned for. But we’re now part of a wider group of companies, with access to a considerably enlarged portfolio of products and services that complement our own seabed-to-shore systems. We expect this to deliver significant operational benefits for our customers across the global energy, ocean science, civil and defence markets.”“Next year will be Sonardyne’s 50th year in business and I’m proud to have played a significant role in the success of the company over the last two decades,” added John. “As we look forward to celebrating that half century milestone with Graham at the helm, our collective sights are focused on the direction we’re headed in at the start of our second half century. As CEO of Sonardyne Group, I’m excited at the prospect of working with Graham and his counterparts across our business to support those who measure, navigate, communicate or explore the world’s waters and oceans, safely, responsibly and more efficiently than ever before.”Graham is an Electromechanical Engineer by background with a first-class degree and Ph.D. He is also a Chartered Engineer, a Fellow of the Institute of Directors (IoD), a Fellow of the Institute of Marine Engineering Science and Technology (IMarEST), and a member of the Society for Underwater Technology (SUT).
The Batesville Lady Bulldogs Golf team has captured the Sectional Crown at The Greensburg Country Club. The host Lady Pirates finish second and The East Central Lady Trojans finish third to qualify for The Regionals.Emma Weiler from The Lady Bulldogs was the Individual Champion. Fellow teammate Josie Meyer was second and Megan Reisman from Greensburg was third. Emerald Simmons from The Oldenburg Lady Twisters qualifies individually to The Regionals.Failed to fetch Error: URL to the PDF file must be on exactly the same domain as the current web page. Click here for more infoRushville was 4th followed by North Decatur, Milan, Jac-Cen-Del, and Oldenburg.The Richmond Lady Red Devils were the team Sectional Champions at The Liberty Country Club in Liberty. The Franklin County Lady Wildcats finish second and The Hagerstown Lady Tigers placed third to advance to The Regionals.Esther Etherington of The Lady Red Devils was the Individual Champion. Camryn Brewer, Gracie Graf, and Nicole Mears from The Lady Wildcats were second and tied for third respectively.Failed to fetch Error: URL to the PDF file must be on exactly the same domain as the current web page. Click here for more infoNortheastern was fourth followed by Connersville, The host Lady Patriots, New Castle, Centerville, and Cambridge City Lincoln.The host Madison Lady Cubs won the Sectionals at the The Sunrise Golf Course in Madison. The Lawrenceburg Lady Tigers were second followed by Scottsburg Warriorettes third to qualify for The Regionals.Keara Eder from The Lady Cubs was the Individual Winner.Failed to fetch Error: URL to the PDF file must be on exactly the same domain as the current web page. Click here for more infoJennings County was fourth followed by Southwestern, Henryville, Switzerland County, Shawe Memorial, and South Dearborn.The best of luck to our area golf teams and individuals at the Regionals at Lapel and Roncalli on Saturday, September 26th.
“When you play in your opponents’ half, in the final third, he is one of the players who can create something special, either through his pass or through his finishing,” said Wenger. “He is two-footed, and that makes him very dangerous.” Wenger added: “Cazorla was out for a long time at the start of the season and had some injury problems. “After that he had an ankle problem and only recently, since mid-December, has he come back to his level.” Wenger felt his side deserved credit for showing patience to finally breaking down what was a determined defensive display from the Cottagers, who are fighting for their top-flight survival. He said: “We were in control for the 90 minutes, but we were a bit one-paced in the first half with our passing. In the second half, when we got up a gear we scored the goals. “We had a few more chances, but overall in games against teams who fight not to go down, they are of course very difficult. Sometimes it is a question of patience.” Arsenal are on the look out for some offensive cover following the season-ending knee injury to England forward Theo Walcott. Press Association Wenger, though, played down suggestions a deal for Juventus’ striker Mirko Vucinic was imminent, with reports representatives from the club had held meetings with the player’s agent. “We are looking at potential possibilities for us to get someone in, but we are not especially in for Vucinic,” Wenger said. “Some people have visual capacities that I don’t have.” The Arsenal manager continued: “We are not on any special case. “I would love to announce something that would excite you and me, but I don’t have the possibility to do it.” With or without any new additions, Wenger feels Arsenal are well set for what looks to be the most exciting championship run in of recent years. “We have played 22 games and have 51 points. If you compare that to any other season you will see that it is one of the best, if not the best ever, so let’s just continue,” the Frenchman said. “We have a good solidarity in the group and we rotate a bit and sometimes great players are on the bench. “You want me to buy more players, but if they sit on the bench you ask me why.” Fulham – who made the expected sweeping changes from their midweek FA Cup third-round replay win over Norwich – had never won in any competition at Arsenal, and have now lost 23 of their visits to north London. Rene Meulensteen’s men remain in deep trouble just a point out of the relegation zone. The Dutch coach, however, remains optimistic. He said: “I couldn’t have asked for anything more at half-time. We knew it would be even harder in the second half because of the quality of players they have. “If you switch off for one moment they can hurt you, and that’s what they did, but there were lots of positives to take from it from our point of view. “You must always see the results and the performances, they are interlinked. “Our performances have been really good, but (we) haven’t had the results.” Meulensteen, who took over from Martin Jol in December, added: “I think we can survive, definitely. The spirit is good, we have got plenty of quality, and I believe the short time I have been in with these players we are improving all the time, working hard. “What we need is a break with a run of results, but that’s not easy because of the opponents we are facing.” With free-scoring Manchester City romping to another big home win as Cardiff were the latest side put to the sword, there was little margin for error from Wenger’s men, who hold a slender one-point lead. After a slow first half, the Gunners finally sparked into life as two quick goals from Cazorla, each dispatched with an instinctive finish – secured what was in the end a comfortable victory. Arsenal manager Arsene Wenger hailed the special talents of Santi Cazorla after the Spain international struck twice in the second half as Fulham were beaten 2-0 to keep the Gunners top of the Barclays Premier League.
One person is dead, and two others were injured after an argument erupted inside a Costco in Southern California.Witnesses said they heard at least six shots sending shoppers racing for the exits and ducking for cover.Police swarmed the Costco after shots were reported at the huge store about 50 miles southeast of downtown Los Angeles.Witnesses say that a man with a mohawk haircut was arguing with someone near a freezer section when he pulled a gun and fired at least six shots.The man involved in the argument was killed, and two other people were wounded, Corona police Lt. Jeff Edwards said.Saturday, Corona police said the victims’ conditions were unknown.The suspected gunman was apprehended, said he was injured and was taken to the hospital, Edwards said.No identities were released at this time.
Martin County Sheriff’s OfficeA 2007 silver Lincoln owned by Donald and Lorraine Smith, who were found dead in the Martin County home on Aug. 28, 2020.Officials are still investigating but are seeking the public’s help and is asking if anyone knows or has seen anyone who was driving the couple’s Lincoln over the last couple of days to notify them. Martin County officials say an elderly couple was found dead inside their home in Martin County on Friday.Detectives are investigating the case as a double homicide.According to reports, a friend of the couple told officials they had not heard from them, and went to go check on them Friday morning. That’s when the bodies were discovered. Deputies arrived to the scene and said they found Donald and Lorraine Smiths’ bodies in a living room with clear signs of trauma.Sheriff William Snyder said the couple’s silver 2007 Lincoln sedan on Jefferson Street in the Golden Gate neighborhood of Stuart.
For all the Latest Sports News News, Cricket News News, Download News Nation Android and iOS Mobile Apps. New Delhi: Former BCCI president Anurag Thakur has said “India should not pay any money to the PCB” ahead of the International Cricket Committee’s (ICC) hearing on the Pakistan’s Cricket Board’s (PCB) claim of Rs 447 crore against India for twice refusing to play a bilateral series. “For number of years, nations didn’t visit Pakistan to play matches. I think no official from India should attend the ICC hearing. India shouldn’t pay money to Pakistan Cricket Board,” Thakur told news agency ANI. Earlier this month, the BCCI said it had hired a Dubai-based law firm and a British lawyer for the October’s ICC three-day hearing.Pakistan has claimed damages of approx Rs 447 crore for India not playing any bilateral cricket with them despite a Memorandum of Understanding (MoU), which guarantees six bilateral series between 2015 and 2023. The BCCI has asserted that the MoU is not binding on them and the PCB failed to honour some of the commitments made in the document.The ICC hearing in the matter is scheduled from October 1 to 3.Also Read | Pakistani helicopter violates Indian airspace in J&K’s Poonch sector, armed forces open fire“The BCCI has hired Dubai-based law firm Herbert Smith Freehills along with British Lawyer QC Ian Mills to represent us at the Dispute Resolution Committee hearing. Since the case is happening in Dubai, we needed a Dubai-based law firm. Also, the ICC follows British law so, QC Ian Mills is on board. We will fight this case till finish,” a senior BCCI official had earlier told news agency PTI.Speaking on the issue, former IPL chairman Rajeev Shukla said that both the cricketing boards should solve the matter among themselves rather than involving ICC in it.”Wherever international matches are organised by the ICC or the Asian Cricket Council, we always play with Pakistan, this time we played at a neutral venue. There is no question of paying money to Pakistan Cricket Board.” Also Read | Kajol reveals Ajay hasn’t watched DDLJ yet; Here’s what Ajay has to sayHe added: “As far as the BCCI versus the Pakistan Cricket Board dispute is concerned, my own view is that both the Boards should resolve it amicably instead of lingering it in the ICC. The BCCI always wanted to play with Pakistan but there are certain issues, we need government’s nod to go to Pakistan to play matches,” Shukla said.(With inputs from PTI)
The Legend Edition 2016 is a two-day event, from August 11 to12th, will focus on youth development and empowerment through a once-in-a-lifetime inspiring experience with Pele.The event will involve football loving teenagers and parents, key figures from various state governments, the corporate sector and the Nigerian Football Federation (NFF).This event will include; a sports clinic (Legend tournament), a Gala Night with Pele and other African football legends; including an auction of Pele memorabilia at the Gala night.Proceeds from the auction will be donated to an eligible local youth football academy.Pele is renowned for many achievements including scoring 1,281 goals in his professional career, receiving an honorary knighthood from Britain’s Queen Elizabeth II, named “Athlete of the Century” and “Player of the Century,” by the International Olympic Committee and FIFA respectively, amongst others.This is will be Pele’s second visit to Nigeria; the first in 1967, was occasioned by a two-day cease fire during the Nigerian Civil War, which allowed the warring sides to watch the Pele and Santos team play an exhibition match in Lagos.WJS is an organisation which provides engaging platforms to facilitate deeper understandings, through conversations that drive nation building consciousness, gender inclusiveness, community development, youth empowerment and ultimately transformative thinking.YEDA is structured to identify, encourage and develop high potential youth become responsible citizens of society as well as ascend to leadership positions within various sectors of the economy/society.Share this:FacebookRedditTwitterPrintPinterestEmailWhatsAppSkypeLinkedInTumblrPocketTelegram Adequate Security has been put in place ahead of the August 10 visit to Nigeria of football icon, Edson Arantes do Nacimento, popularly known as Pele.At a press conference on Friday at the Astro Turf, Ikoyi, Lagos to herald the arrival of the Brazilian, who is regarded by many as the best footballer of all time, the organisers said everything had been put in place to make his visit a huge success.The Winihin Jemide Seris (WJS), along with Youth Experience Days Africa (YEDA), will be facilitating the WJS/YEDA Legend Edition 2016 with Pele.
Researchers from the Keck School of Medicine have found a way to genetically modify mice so the rodents’ immune systems act like human immune systems, a discovery that will impact medical testing.Doctors Weiming Yuan, Xiangshu Wen, Seil Kim and Agnieszka Lawrenczyk published the study this month in the Proceedings of the National Academy of Sciences. The research took about two years and the project will be completed within four years.Yuan, the project’s chief investigator, began work on the mice a few years ago, after he recognized that current clinical trials were not successful. Yuan attributed this to minor differences between human and rodent immune systems. This difference led him to attempt to humanize the mouse model.“Making a mouse is a challenging project,” Yuan said. “This will be helping a lot of scientists to further clinical trials.”The mice contribute to research toward finding better treatments for cancer. When tested on mice, the drug α-GalCer successfully rid the animal of cancerous cells. The same results, however, were not obtained when the medication was used on human subjects, showing differences between the two species’ immune systems.The mice modification project required the successful insertion of a new functioning gene. This type of modification is far more challenging than so-called “knock-out” genetic modification, which is modification that works by eliminating a gene’s function. Yuan said the next step will be to further humanize the T-cell receptor, which activates lymphocytes that initiate immune system responses.The team used the difficulty of the project as motivation to succeed. Yuan said they were all very enthusiastic about their research despite difficulty working with the small size of their grant.“[We] definitely needed more funding — it’s the practical challenges,” Yuan said. “Lots of scientists are concerned about the funding situation.”The team hopes to further their work in the humanization of the rodents’ immune system.“We will branch out, but right now we have more work to further humanize the mice,” Yuan said. “We still have quite a lot of work to do before we branch out.”The dedication and enthusiasm of the team is only gaining momentum. “The future model will be even more reliable,” Yuan said.